Practical Considerations for Detecting NTRK Gene FusionsVideo Categories: NTRK Gene Fusions
Dr Ezra Cohen of UC San Diego, La Jolla, CA; Dr Mary Fidler of Rush University Medical Center, Chicago, IL; and Dr Arturo Loaiza-Bonilla of the Comprehensive Care and Research Center, Philadelphia, PA, review molecular methodologies and factors to consider in the identification of TRK fusion–positive tumors.
Dr Wainberg and Dr Gerson review why providers are using combination therapies and the eventual goal of investigators to hit specific targeted cells.
Drs. Roy Herbst and David Rimm review some of the problems associated with obtaining enough tissue to perform biomarker testing, the need to triage tissue to ensure that standard of care tests are completed, and the potential role of liquid biopsies