October 2015, Vol. 4, No. 5
Genetic Counseling in Personalizing Care: A New Department in PMOLetter to Our Readers
I am pleased to announce a new department in PMO, Genetic Counseling. In each issue, PMO editorial board member Cristi Radford, MS, CGC, of the Moffitt Cancer Center will contribute an impactful article. In this issue, you will read about BRCA1/2 testing for any patient with pancreatic adenocarcinoma. If you have an intriguing case to share, I encourage you to submit it to our Editorial Director at firstname.lastname@example.org.
The mission of our journal is to provide a bridge between academic research and practicing clinicians by demonstrating the immediate implications of precision medicineâincluding advances in molecular sequencing, targeted therapies, and new diagnostic modalitiesâto the management of patients with cancer, offering oncologists, oncology nurses, payers, researchers, drug developers, policymakers, and all oncology stakeholders the relevant practical information they need to improve cancer outcomes. Improved outcomes lie in the ability to administer effective therapies. Our ability to prescribe effective therapies has more and more become reliant on our understanding of the molecular biology of the tumor microenvironment as well as the genomic and genetic information of the patient.
To this end, this month we offer an intriguing interview with Nazneen Aziz, PhD, of the Phoenix Childrenâs Hospital revealing how genetic, genomic, and biomarker information is being put to work to improve outcomes for patients. We also present a case study on molecular pathways in nonâsmall cell lung cancer as well as several other relevant articles on the personalized approach to caring for patients with cancer.
As always, thank you for your loyal readership. We hope the addition of the genetic counseling department will be of value to you in your practice.
Al B. Benson III, MD, FACP, FASCO
Coeditor in Chief
Personalized Medicine in Oncology
Molecular Biomarkers Having Huge Impact on Cancer Clinical Trials
Increasingly, genomic alterations are being recognized and targeted for clinical trials. Improving clinical trial accrual in this environment may require multiple histology basket trials that increase the percentage of patients with âactionableâ alterations, said Funda Meric-Bernstam, MD, at PMO Live 2015. The implications for the use of predictive markers for [ Read More ]
Looking into the Future of Lung Cancer Research
Each year, the Bonnie J. Addario Lung Cancer Foundation (ALCF) recognizes luminaries in the quest to cure lung cancer with the Addario Lectureship Award. This year, Fred R. Hirsch, MD, PhD, Professor of Medicine and Pathology, University of Colorado School of Medicine, Denver, delivered his keynote lecture on the many [ Read More ]