May 2013, Vol 2, No 3

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Personalized Medicine in Oncology: Providing Insights to Optimally Utilize Personalized Medicine Concepts

Greg Kalemkerian, MD


Dear Colleague,

I want to welcome you to this issue of Personalized Medicine in Oncology (PMO) with a few facts concerning personalized medicine (PM):

  • 79% of late-stage oncology pipeline are targeted therapies
  • Molecular profiling is driving many new targeted cancer therapeutics, with over 500 compounds coming soon, and 140 targets in development
  • Companion diagnostics are playing an increasingly greater role in cancer product launches

Taken alone, any of these developments would call for intensified efforts to educate practicing oncologists in PM systems and resources. Taken together, they are a clarion call for extraordinary measures to ensure that this happens.

PM is a medical art form requiring awareness of key diagnostic and therapeutic resources. The demand for excellence by patients and caregivers is matched by the demand for value by payers and purchasers. All of these parties recognize cancer as the deadly enemy and will go to great lengths to obtain patient-
centered, value-based care.

Enter PMO. We bring oncologists the insights into the key developments in PM needed to raise their clinical skills and stay competitive through the expert use of the breakthrough treatments and diagnostics. The greatest clinical armamentarium is meaningless without knowledge of its proper deployment…and that is what PMO brings to oncologists in every issue. Our balanced reviews and editorials give today’s oncologists the insight they need to optimally utilize the products that bring value to the patient-centered cancer care model that is taking shape before our eyes.


Greg Kalemkerian, MD
University of Michigan
PMO Board Member

The Last Word - May 24, 2013

The MHealth Factor: A Bioinformatics Platform for Arming the Oncology Personalized Medicine Revolution

Personalized medicine (PM) applied to cancer diagnosis and treatment is really all about information: discovering it, synthesizing it, analyzing it, translating it to cancer pathophysiology, and finally sharing it with those who need to know what is going on inside the tumors. The rise of PM skill sets, as I [ Read More ]

Uncategorized - May 24, 2013

Current Treatment of Myelofibrosis: How Far We Have Come and How Far We Have Yet to Go

At the 2012 conference of the Global Biomarkers Consortium, which took place March 9-11, 2012, in Orlando, Florida, Charles Schiffer, MD, from the Barbara Ann Karmanos Cancer Institute and Wayne State University in Detroit, Michigan, discussed the management of myeloproliferative neoplasms. Major advances in understanding the biology of hematologic malignancies, [ Read More ]