June 2016, Vol. 5, No. 5

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Personalized Medicine in Oncology: Expanding Our Knowledge of Precision Medicine

Personalized Medicine in Oncology: Expanding Our Knowledge of Precision Medicine

Letter to Our Readers

Benson-pic-98pxDear Colleague,

This issue of Personalized Medicine in Oncology (PMO) is a testament to how far we’ve come in our understanding of, and novel approaches to, the treatment of cancer. Armed with knowledge of molecular biomarkers, genetic mutations, genomics, immunotherapeutics, and targeted therapies, we are better able to treat patients with cancer to obtain longer survival and higher quality of life than ever before.

This month, Christos Fountzilas, MD, and Virginia G. Kaklamani, MD, DSc, provide a review of BRAF mutations and implications when considering treatment strategies for patients with this mutation.

In our Interview with the Innovators department, we talk with Chief Scientific Officer Paul W. Dempsey, PhD, and Chief Medical Officer Paul Y. Song, MD, of Cynvenio about their multiple-template strategy that analyzes DNA from circulating tumor cells, circulating cell-free DNA in blood, and tissue biopsies, as well as the initiation of their clinical trial in triple-negative breast cancer. We hope you find our exchange insightful and helpful.

Is there a topic you would like to see discussed in PMO? An innovator in the oncology community you’d like to have interviewed? Please contact us with your comments and request at editorial@the-lynx-group.com.

As always, thank you for your loyal readership. It is our pleasure to serve you in your quest to provide personalized medicine to your patients.


Coeditor in Chief
Personalized Medicine in Oncology

AACR - June 16, 2016

Multivitamin Use During Chemotherapy May Reduce Risk of Peripheral Neuropathy

Multivitamin supplement use was associated with a reduction in chemotherapy-associated peripheral neuropathy in a subanalysis of the SWOG S0221 trial. Patients who were using multivitamins before chemotherapy had 40% less neuropathy, and those using them during or after treatment had a 23% reduced risk. The results were reported at the [ Read More ]

Clinical Trials Tracker - June 16, 2016

Select Ongoing Trials Currently Enrolling Patients with Colorectal Cancer

The following are a selection of key clinical trials that are currently recruiting patients for inclusion in investigations of new therapies or new combinations of available therapies for patients with colorectal cancer. Each clinical trial description includes the NLM Identifier to be used as a reference with ClinicalTrials.gov. The information [ Read More ]