May 19, 2016
August 2012, Vol 1, No 3
New Targeted Therapies and New Biomarkers Explored at ASCO 2012
Below are some highlights of presentations at the 2012 ASCO Annual Meeting related to targeted therapies and personalized (precision) medicine. T-DM1 The anti-body drug conjugate T-DM1 significantly prolonged progression-free survival (PFS) compared with standard capecitabine/lapatinib therapy for treatment of advanced HER2-positive breast cancer in the EMILIA trial (Abstract LBA1). Median [ Read More ]
UncategorizedProstate Cancer Roundup
Nearly 3000 abstracts were selected for presentation at the recent ASCO 2012 Annual Meeting, many of them related to some aspect of personalized medicine. Below are some highlights selected from the meeting that focus on potential genomic predictors of aggressive versus indolent disease and on potential biomarkers. 6-Gene Model Identifies [ Read More ]
UncategorizedIncorporating Genomics Into Practice:
An Interview with Kimberly J. Popovits
Genomic Health, Inc, located in Redwood City, California, is a global cancer company founded in 2000. Genomic Health currently offers patients the Oncotype DX Breast Cancer Assay and the Oncotype DX Colon Cancer Assay. Genomic Health maintains that the key to effectively using clinical genomics to improve cancer treatment and [ Read More ]
Interview with the InnovatorsFacilitating the Next Generation of Precision Medicine in Oncology
Key Points Key stakeholders are increasingly considering new measures to protect and advance innovation and investment in diagnostics Efforts are under way to establish more appropriate and least burdensome regulatory policies to address stakeholder concerns specific to in vitro diagnostic tests FDA is concerned with the risk of false-positive and [ Read More ]
UncategorizedWhich Breast Cancer Patients Should Receive Adjuvant Chemotherapy?
At the 2012 conference of the Global Biomarkers Consortium, which took place March 9-11, 2012, in Orlando, Florida, Alvaro Moreno-Aspitia, MD, from the Mayo Clinic in Jacksonville, Florida, discussed the use of personalized therapy in the management of breast cancer. Key Points A number of decision-making tools have become available [ Read More ]