May 19, 2016
Faculty Perspectives in Chronic Pain, Part 3 of 5 In Vitro and Clinical Assessments of Abuse-Deterrent Formulations for Chronic Pain
In Vitro and Clinical Assessments of Abuse-Deterrent Formulations for Chronic Pain
Chronic noncancer pain is now considered a global epidemic and a public health problem in the United States, partly owing to its prevalence, underdiagnosis, and undertreatment.1 The resultant and unprecedented increase in the use of opioids has become a national concern because of parallel increases in the misuse, abuse, and [ Read More ]
Clinical Assessment of Abuse-Deterrent Formulations
In 1985 and 1996, the World Health Organization issued guidelines on cancer pain relief.1 The ethical mandate for pain treatment has been extended to chronic nonmalignant pain, and some have argued that this type of pain produces suffering similar to that of cancer pain but with a higher prevalence and [ Read More ]
The Tip of the Iceberg
For as long as prescription opioids have been available for the treatment of patients with chronic, noncancer pain, misuse, abuse, and diversion of these agents have been ongoing issues. The abuse of prescription opioids may lead to high rates of morbidity and mortality, and may be associated with significant increases [ Read More ]
In Vitro and Clinical Assessments of Abuse-Deterrent Formulations in the Management of Chronic Pain
Opioid abuse and diversion are important issues for all payers, as they must balance access to opioids for those who truly need treatment with the potential that these drugs may not be used as intended. This issue is supported by the fact that in 2010, there were 16,651 opioid-related deaths [ Read More ]