The Lynx Group

National Comprehensive Cancer Network

Test for EGFR Mutation in All Patients with NSCLC
Matching Treatment to Molecular Alteration Yields Best Outcomes

Tyrosine kinase inhibitors (TKIs) are the mainstay of treatment for patients with EGFR mutation–positive non–small cell lung cancer (NSCLC), according to the most recent guideline on management of NSCLC issued by the National Comprehensive Cancer Network (NCCN). Version 4.2016 of the guideline recommends EGFR testing as part of broader molecular [ Read More ]

Panel Examines Effects of Healthcare Policy in an Election Year

The chances for further policy in healthcare during an election year are minimal, said panelists during a roundtable discussion at the National Comprehensive Cancer Network 21st Annual Conference. The exception may be the Medicare Part B demonstration project for provider reimbursement for infused and injected drugs. Moderators of the panel [ Read More ]

New MM Guideline Expands Patients Eligible for Treatment

The population of patients with multiple myeloma (MM) who are eligible for therapy has been expanded to asymptomatic patients with certain features under the most recent National Comprehensive Cancer Network (NCCN) guideline (Version 3.2016). Also, among 7 new drug approvals in 2015 with indications for the treatment of MM, new [ Read More ]

Immunotherapy Takes Center Stage in NCCN Advanced Melanoma Guideline

The revised guideline (Version 2.2016) for the management of advanced melanoma, released by the National Comprehensive Cancer Network (NCCN), shows increasing appreciation for the use of immune checkpoint inhibitors and targeted agents, as more data establish these drug classes as having superior efficacy to traditional chemotherapy. “We’ve seen the approval [ Read More ]

Checkpoint Blockade: Durable Responses in Lung and Kidney Cancers and Metastatic Melanoma

A new guideline from the National Comprehensive Cancer Network (NCCN) incorporates nivolumab as subsequent therapy for metastatic squamous non–small cell lung cancer (NSCLC) following its recent FDA approval. In advanced renal cell carcinoma (RCC), immune checkpoint blockade may provide a new approach to treat this disease, with durable responses achieved [ Read More ]

Sign me up!