Genomic Instability Score Predicts Survival in Ovarian Cancer
A higher score on a composite index of homologous recombination deficiency (HRD) correlated with improved progression-free survival (PFS) and overall survival (OS) in ovarian cancer treated with platinum-containing chemotherapy, results of a tissue-based validation study showed. An HRD score that met or exceeded the predefined threshold reduced the hazard ratio [ Read More ]