September 2014, Part 3 - Uncategorized
Overview of Cervical Cancer and HPV Cervical cancer was once the leading cause of death for women, but progress has shown how successful screening for early disease can be in reducing deaths from cancer. Thanks to the studies of George Papanicolaou aided by his assistant Andromache Mavroyenous (who was also [ Read More ]
September 2014, Part 3 - Uncategorized
Overview Cytokines are familiar to the oncologist as the glycoprotein messengers of the immune system and beyond. Their role in cancer treatment has been firmly established since the late 1980s, when investigators reported that interleukin (IL)-2 administration plus adoptive transfer of lymphokine-activated killer cells were effective treatment for refractory solid [ Read More ]
September 2014, Part 3 - Colorectal Cancer
Although it affects 2 distinct anatomical sites, colorectal cancer is often regarded as a single entity, and treatment plans for colon cancer and rectal cancer are quite similar.1,2 Cases of colorectal cancer comprise more than 8% of newly diagnosed cancer cases and nearly 9% of all cancer deaths in the [ Read More ]
June 2014, Part 2 - Uncategorized
Immune checkpoints modulate immune responses by providing signals that attenuate T cells. The importance of immune checkpoints in cancer treatment has been underscored by recently approved therapies. For example, ipilimumab is a monoclonal antibody directed against the cytotoxic T-lymphocyte antigen (CTLA)-4. Normally, CTLA-4 would prevent the costimulatory activity of CD80 [ Read More ]
Overview Melanoma cases make up nearly 5% of new cancers diagnosed in the United States, making it the fifth most common type of cancer in this country.1 With the introduction of targeted therapy, melanoma treatment has undergone rapid changes in recent years, resulting in an overall 5-year survival rate of [ Read More ]
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