May 19, 2016
December 2015, Vol. 4, No. 6
Sample Size Calculation for Single-Arm Phase 2 Prostate Cancer Trials
Prostate cancer remains one of the major health issues for men worldwide and is the second leading cause of cancer-related death in males in the United States…
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Inherited Colorectal Cancer: POLE and POLD1
The association of POLE and POLD1 with colorectal cancer risk was demonstrated in 2013. Palles and colleagues studied families with a dominant pattern of inherited colorectal cancer and multiple adenomas through whole genome sequencing.1 Through these efforts, they identified germline mutations in POLE and POLD1 as high-penetrance genes predisposing to [ Read More ]
Letter to Our Readers - December 28, 2015
Personalized Medicine in Oncology: Disseminating Essential Information
Dear Colleague,On behalf of all of us at Personalized Medicine in Oncology (PMO), I’d like to offer our warmest wishes to you this holiday season and our thanks for your loyal readership throughout 2015. Over this past year, we have witnessed advances in our knowledge of tumor biology, biomarkers, and [ Read More ]