December 2015, Vol. 4, No. 6

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Sample Size Calculation for Single-Arm Phase 2 Prostate Cancer Trials

Prostate Cancer

Prostate cancer remains one of the major health issues for men worldwide and is the second leading cause of cancer-related death in males in the United States…

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Pediatric Oncology - December 28, 2015

Commentary: Treatment for Children Receiving Emetogenic Chemotherapy

Chemotherapy-induced nausea and vomiting is a frequent and potentially treatment-limiting complication of cancer therapy in both adults and children. However, pediatric oncologists have been keenly aware that while effective regimens have been developed for adults, effective regimens for children receiving emetogenic chemotherapy have been lacking.1-3 On September 2, 2015, the [ Read More ]

Interview with the Innovators - December 28, 2015

The Current Landscape in Melanoma Treatment

An Interview with Jeffrey Infante, MD, of Sarah Cannon Research InstituteThe COMBI-d and COMBI-v trials showed that treating BRAF V600 mutation–positive metastatic melanoma with the combination of da­brafenib plus trametinib resulted in a significant increase in overall survival and a 33% reduction in the risk of progression or death compared [ Read More ]