Interview with the Innovators

Personalized Medicine and Value:

An Interview with Faculty at the Fourth Annual Conference of the Association for Value-Based Cancer Care

C. Daniel Mullins, PhD, is a professor and former department chair of the Pharmaceutical Health Services Research Department at the University of Maryland School of Pharmacy. Linda Bosserman, MD, is a community medical oncologist at Wilshire Oncology. Andrew Stainthorpe, PhD, is associate director of the National Institute of Health and [ Read More ]

The Treatment of Relapsed Metastatic Melanoma Using a Novel Immunotherapy Combination:

An Interview with Mario Sznol, MD

During the 2014 annual meeting of the American Society of Clinical Oncology (ASCO), Mario Sznol, MD, presented Abstract LBA9003—Survival, Response Duration, and Activity by BRAF Mutation Status of Nivolumab and Ipilimumab Concurrent Therapy in Advanced Melanoma—on behalf of his colleagues and fellow investigators. The presentation summarized objectives, methods, and long-term [ Read More ]

Implementing Global Healthcare: Partners In Health and the Rwandan Cancer Center Initiative

Partners In Health (PIH) was founded in 1987 by Ophelia Dahl; Paul Farmer, MD, PhD; Jim Kim, MD, PhD; Todd McCormack; and Thomas J. White to deliver healthcare to residents of Haiti. In the 27 years since then, PIH has launched healthcare projects around the world. Its mission is to [ Read More ]

Perspectives on the Landscape of Personalized Medicine

An Interview with Gail E. Herman, MD, PhD; Barbara L. McAneny, MD; and Charles L. Sawyers, MD

Gail E. Herman, MD, PhD, is President of the American College of Medical Genetics and Genomics (ACMG).Barbara L. McAneny, MD, is Chief Executive Officer of New Mexico Cancer Center, New Mexico Oncology Hematology Consultants, Ltd.Charles L. Sawyers, MD, is Chair of the Human Oncology & Pathogenesis Program at Memorial Sloan [ Read More ]

A Breakthrough Treatment for ALL and CLL: The New Biologic Agent, CTL019

An Interview With David L. Porter, MD, of the University of Pennsylvania

David L. Porter, MD, is Jodi Fisher Horowitz Professor in Leukemia Care Excellence in the Perelman School of Medicine at the University of Pennsylvania; and Director, Blood and Marrow Transplantation at the Abramson Cancer Center.The number of patients was small and the therapy still investigational, but the results of research [ Read More ]

Empowering the Practice of Personalized Medicine: The Evolving Role of Pathology in Cancer Diagnostics

An Interview With Pranil K. Chandra, DO PathGroup is a diagnostic and clinical service company providing comprehensive anatomic, clinical, and molecular pathology services. They are committed to providing diagnostic expertise, precision technologies, and innovative services to give physicians and their patients personalized information for targeted therapies that lead to the [ Read More ]

Family With a Risk of Cancer Tries to Change Its Destiny

A Controversial Procedure Lets Couples Select Embryos Free of a Genetic Mutation To shield any future children from the fear she harbors of getting breast cancer, Katie Dowdy underwent a controversial procedure to select embryos of hers that were free of a genetic mutation linked to the disease. Deciding to [ Read More ]

Case Study: Molecular Profiling in Acute Myeloid Leukemia

At the 2013 conference of the Global Biomarkers Consortium, which took place October 4-6, 2013, in Boston, MA, Mark J. Levis, MD, PhD, associate professor, Department of Oncology, Medicine, and Pharmacology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD, discussed the use of personalizing therapy in the management [ Read More ]

Partners HealthCare Center for Personalized Genetic Medicine: Utilizing Genetics and Genomics to Improve Care of Patients

An Interview With Scott T. Weiss, MD, MS, and Heidi L. Rehm, PhD

Harvard Medical School and Partners HealthCare System established the Harvard-Partners Center for Genetics and Genomics (HPCGG) in 2001. The center was launched in recognition of the excitement of the Human Genome Project and as an early commitment to the importance of genetic and genomic knowledge in human health. HPCGG offered [ Read More ]

Personalized Medicine and the Biopharmaceutical Industry: The Marrying of Science, Research, and Policy

An Interview With Dr William Chin of the Pharmaceutical Research and Manufacturers of America

Dr Chin is an internist and endocrinologist who spent much of his early career studying the molecular mechanisms of hormonal control of gene expression. After 25 years in academia, including positions as investigator at Howard Hughes Medical Institute, Professor of Medicine at Harvard Medical School, and Chief, Division of Genetics [ Read More ]

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